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Single cell analysis enables meaningful discoveries

Bulk sequencing averages readouts, missing critical details driving complex biology.

Single cell sequencing allows scientists to see the unique gene expression patterns of each cell. This view more fully characterizes tissue heterogeneity, revealing the rare cell types that have big consequences in health and disease.

Get to know the method changing how we see biology

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New to single cell RNA-seq?

Explore our beginner's guide to single cell biology

The Chromium Advantage

  • Higher gene sensitivity and up to 80% cell recovery efficiency.
  • Enhanced detection of challenging cell types, including neutrophils.
  • Reduce hands-on time and lower the risk of errors with instrument-supported automation of the most critical workflow steps.
  • Produce higher quality libraries that can sequenced at lower depths.
  • Backed by 10 years, over 2,200 patents, and >$1.5B in R&D investment.

See more reasons why top labs trust Chromium

Innovations developed for your success at every step

Access more sample types

Profile fresh, frozen, or fixed samples—even FFPE—with optimized protocols for proven performance

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Automate critical steps to reduce error

Produce up to 2.56M barcoded partitions in just minutes, with up to 80% cell recovery

Construct high-quality sequence-ready libraries

Generate libraries with up to 95% usable reads, letting you detect more genes at lower sequencing costs

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Analyze & discover with ease

Process and visualize your data with powerful software tools—no bioinformatics experiences required

Performance, reproducibility & cost-efficiency built in
GEM-X innovations plus push-button automation deliver the world's fastest, highest quality cell partitioning & barcoding. Get the most out of your research budget with improved cell recovery and lower sequencing depth requirements.

Broad, flexible portfolio of assays
Whether you opt for whole transcriptome or protein coding gene coverage, you can be confident that you'll get high-quality data every time.

Universal Gene expression

Species agnostic. Maximum versatility.

Whole transcriptome coverage
  • Delivers broadest set of information, including isoforms, SNPs, etc.
Multiomic readouts from the same cell
  • 3' or 5' gene expression

  • TCR/BCR

  • Protein

  • CRISPR

For cost-effective studies
  • Up to 160,000 cells (1-8 samples) per run, plus lower cost of <$565/sample
Products
  • Universal 3' Gene expression
  • Universal 5' Gene expression

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Flex Gene expression

Fix, batch, and run on your schedule.

Protein coding gene coverage
  • Performs well with low-quality and FFPE samples
Multiomic readouts from the same cell
  • Gene expression

  • Protein

  • CRISPR

Highest throughput option
  • Up to 2.56M cells (1-16 samples) per run, for less than $0.01/cell
Products
  • Flex Gene expression

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Epi Chromatin

Unmask epigenomic profiles.

ATAC-seq chemistry
  • Explore open chromatin regions

  • link directly to 3' gene expression (Multiome kit)

Multiomic readouts from the same cell
  • Chromatin accessibility

  • 3' gene expression

Scalable nuclei preparation
  • Profile up to 80,000 nuclei (1-8 samples) per run
Products
  • Epi ATAC
  • Epi Multiome

Amplify your research gains
Access the greatest application breadth on the market with superior multiomic integration and 40+ demonstrated protocols.

Gene expression

Characterize the unique transcriptomic profiles of each cell in your sample

Explore gene expression

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Immune profiling

Obtain functional data for antibody/TCR discovery

Read up on immune profiling

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CRISPR screening

Directly link CRISPR guide RNAs to the resulting perturbed phenotypes

Learn more about CRISPR screening

Bring Chromium to your lab
Explore the resources below to learn more about your options and how to get started.


A beginner’s guide to single cell RNA-seq

Practical considerations and best practices for getting started

Unlock the full spectrum of biology
Expand your Chromium Single Cell insights by combining by adding spatial context to the whole transcriptome or targeted genes.

Unlock the full spectrum of biology

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