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Single cell analysis enables meaningful discoveries
Bulk sequencing averages readouts, missing critical details driving complex biology.
Single cell sequencing allows scientists to see the unique gene expression patterns of each cell. This view more fully characterizes tissue heterogeneity, revealing the rare cell types that have big consequences in health and disease.
Get to know the method changing how we see biology
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New to single cell RNA-seq?
Explore our beginner's guide to single cell biology
The Chromium Advantage
- Higher gene sensitivity and up to 80% cell recovery efficiency.
- Enhanced detection of challenging cell types, including neutrophils.
- Reduce hands-on time and lower the risk of errors with instrument-supported automation of the most critical workflow steps.
- Produce higher quality libraries that can sequenced at lower depths.
- Backed by 10 years, over 2,200 patents, and >$1.5B in R&D investment.
See more reasons why top labs trust Chromium
Innovations developed for your success at every step
Access more sample types
Profile fresh, frozen, or fixed samples—even FFPE—with optimized protocols for proven performance
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Automate critical steps to reduce error
Produce up to 2.56M barcoded partitions in just minutes, with up to 80% cell recovery
Construct high-quality sequence-ready libraries
Generate libraries with up to 95% usable reads, letting you detect more genes at lower sequencing costs
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Analyze & discover with ease
Process and visualize your data with powerful software tools—no bioinformatics experiences required
Performance, reproducibility & cost-efficiency built in
GEM-X innovations plus push-button automation deliver the world's fastest, highest quality cell partitioning & barcoding. Get the most out of your research budget with improved cell recovery and lower sequencing depth requirements.
Broad, flexible portfolio of assays
Whether you opt for whole transcriptome or protein coding gene coverage, you can be confident that you'll get high-quality data every time.
Universal Gene expression
Species agnostic. Maximum versatility.
Whole transcriptome coverage
- Delivers broadest set of information, including isoforms, SNPs, etc.
Multiomic readouts from the same cell
3' or 5' gene expression
TCR/BCR
Protein
CRISPR
For cost-effective studies
- Up to 160,000 cells (1-8 samples) per run, plus lower cost of <$565/sample
Products
- Universal 3' Gene expression
- Universal 5' Gene expression
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Flex Gene expression
Fix, batch, and run on your schedule.
Protein coding gene coverage
- Performs well with low-quality and FFPE samples
Multiomic readouts from the same cell
Gene expression
Protein
CRISPR
Highest throughput option
- Up to 2.56M cells (1-16 samples) per run, for less than $0.01/cell
Products
- Flex Gene expression
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Epi Chromatin
Unmask epigenomic profiles.
ATAC-seq chemistry
Explore open chromatin regions
link directly to 3' gene expression (Multiome kit)
Multiomic readouts from the same cell
Chromatin accessibility
3' gene expression
Scalable nuclei preparation
- Profile up to 80,000 nuclei (1-8 samples) per run
Products
- Epi ATAC
- Epi Multiome
Amplify your research gains
Access the greatest application breadth on the market with superior multiomic integration and 40+ demonstrated protocols.
Gene expression
Characterize the unique transcriptomic profiles of each cell in your sample
Explore gene expression
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Immune profiling
Obtain functional data for antibody/TCR discovery
Read up on immune profiling
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CRISPR screening
Directly link CRISPR guide RNAs to the resulting perturbed phenotypes
Learn more about CRISPR screening
Bring Chromium to your lab
Explore the resources below to learn more about your options and how to get started.
A beginner’s guide to single cell RNA-seq
Practical considerations and best practices for getting started
Unlock the full spectrum of biology
Expand your Chromium Single Cell insights by combining by adding spatial context to the whole transcriptome or targeted genes.
Unlock the full spectrum of biology